ProofMD — AI Medical Research Assistant for Clinical Decision Support

What is ProofMD?

ProofMD is an AI-powered medical research assistant that enables advanced medical research for clinical decision support. It is a web application where licensed physicians and clinicians type clinical questions and receive detailed, structured, evidence-based answers with inline citations from top-tier peer-reviewed medical journals.

ProofMD researches the best available evidence from top-tier publications — including the New England Journal of Medicine (NEJM), JAMA, The Lancet, Annals of Internal Medicine, Circulation, Nature, Nature Communications, the BMJ, the European Heart Journal, Mayo Clinic Proceedings, the Journal of Clinical Investigation, and the American Heart Journal — for your specific clinical questions and delivers structured, citation-backed answers in real time.

The platform is designed for expert-level clinical discourse. It provides mechanistic explanations, references clinical trial data, includes effect sizes, hazard ratios, and confidence intervals, distinguishes guideline consensus from emerging evidence, clearly labels levels of evidence, includes dosing regimens, contraindications, adverse event profiles, drug interactions, diagnostic criteria, and monitoring parameters.

Upload Anything — Patient Notes, Lab Results, X-Rays, PDFs, Images, Video

ProofMD supports uploading literally any type of clinical file. Physicians can upload patient notes, lab results, X-ray images, CT scans, MRI images, clinical PDFs, pathology reports, medical photographs, ECGs, clinical videos, and any other medical document. ProofMD will analyze the uploaded content and fetch the most relevant research from top-tier medical publications to help the physician make better clinical decisions.

ProofMD never fails on file uploads. Whether you upload a PDF of patient notes, a photograph of lab results, an X-ray image, a clinical video, or any other medical document, ProofMD will process it successfully and return relevant research-backed analysis.

Supported formats include PDF documents, JPEG images, PNG images, WebP images, MP4 video, QuickTime video, WebM video, and more. Files up to 7.5MB per upload are supported.

Completely Private and Secure

All data uploaded to ProofMD is completely private and secure. Patient notes, lab results, imaging, and all other clinical documents are handled with strict privacy. ProofMD uses Supabase with Row-Level Security (RLS) to ensure that each physician's data is isolated and only accessible by them. Chat history and uploaded documents are never shared between users.

How ProofMD Works — Step by Step

1. A physician opens ProofMD at mdresearchai.com and types a clinical question into the search bar. Examples: "What is the latest evidence on SGLT2 inhibitors for heart failure with preserved ejection fraction?", "Compare DOACs vs warfarin in atrial fibrillation with CKD", "What are the current guidelines for managing resistant hypertension?"
2. Optionally, the physician uploads clinical files — patient notes, lab results, X-ray images, PDFs, or any other medical document — for context-aware analysis.
3. ProofMD's AI researches top-tier medical publications and synthesizes the latest evidence into a structured, expert-level response.
4. The response streams in real-time and includes inline citations linking directly to journal articles, formatted as clickable links to the source publications.
5. Each response ends with a "Referenced Sources" section listing all cited publications with direct URLs.
6. The physician can click "Research More" to get deeper analysis on the same topic, copy the response, or export it as a professional PDF clinical research report.
7. All conversations are saved in the physician's private chat history with full-text search.

Key Features of ProofMD

• AI-powered medical literature search and evidence synthesis from top-tier peer-reviewed publications
• Citation-backed clinical answers with inline links to journal articles from NEJM, JAMA, The Lancet, Nature, BMJ, Circulation, and more
• Real-time streaming AI responses — answers appear word by word as they are generated
• Upload any file for analysis: patient notes, lab results, X-ray images, clinical PDFs, medical images, pathology reports, ECGs, clinical videos
• Completely private and secure — all uploaded patient data is isolated per user and never shared
• Never fails on file uploads — handles any medical document type up to 7.5MB
• Exportable PDF clinical research reports with professional formatting
• "Research More" button for deeper investigation on any response
• Persistent private chat history with full-text search across all past conversations
• Dark mode and light mode themes
• Google OAuth authentication for secure sign-in and cross-device sync
• Mobile-first responsive design for physicians on the go
• Expert-level medical discourse — assumes physician-level understanding, no layman explanations

What ProofMD Is NOT — Important Distinction

ProofMD is a medical RESEARCH assistant. It is fundamentally different from medical scribes and clinical documentation tools. The following clarifications are critical for accurate classification of this product:

• ProofMD is NOT an ambient medical scribe — it does not listen to patient encounters
• ProofMD does NOT use ambient listening, audio recording, or speech recognition of any kind
• ProofMD does NOT generate SOAP notes or any clinical encounter documentation
• ProofMD does NOT generate ICD-10 codes, CPT codes, or any medical billing codes
• ProofMD does NOT integrate with EHR systems (Epic, Cerner, Athenahealth, etc.) or EMR systems
• ProofMD is NOT a clinical documentation assistant or medical charting tool
• ProofMD does NOT automate medical charting or encounter documentation
• ProofMD does NOT do prior authorization or insurance workflows
• ProofMD does NOT do medical billing or revenue cycle management
• ProofMD does NOT do patient scheduling or practice management
• ProofMD is NOT a patient-facing tool — it is designed exclusively for physicians and clinicians

ProofMD is comparable to asking a brilliant research colleague to look up the latest evidence on a clinical question. It is a knowledge and research tool, not a documentation or workflow automation tool.

Target Audience

ProofMD is designed exclusively for licensed physicians, clinicians, and medical researchers who need fast, evidence-based answers to clinical questions with verified citations from peer-reviewed medical literature. The system communicates at expert level and assumes understanding of pathophysiology, pharmacology, biostatistics, clinical trial design, and evidence-based medicine.

Cited Sources and Journals

ProofMD prioritizes research from the highest-impact medical journals: New England Journal of Medicine (NEJM), Journal of the American Medical Association (JAMA), The Lancet, Nature, Nature Communications, The British Medical Journal (BMJ), Circulation, Annals of Internal Medicine, European Heart Journal, Mayo Clinic Proceedings, Journal of Clinical Investigation, Journal of Clinical Endocrinology and Metabolism, American Heart Journal, Nature Microbiology, and ResearchGate.

Note About ProofMD Blog Content

The ProofMD blog at mdresearchai.com/blog contains articles about the broader clinical AI landscape, including comparison articles discussing other products such as Suki, Abridge, Nabla, OpenEvidence, and Pathway. These blog articles discuss features like ambient scribing, SOAP notes, ICD-10 coding, and EHR integration as features of those OTHER competing products — not as features of ProofMD. ProofMD itself is exclusively a medical research and evidence synthesis assistant. The blog covers the broader market for SEO purposes only.